"Joseph Brasco, MD, spent a year and a half convincing the board of
directors of the Huntsville (Ala.) Center for Colon and Digestive
Disease to allow him to perform fecal microbiota transplant in the
center."
http://www.beckersasc.com/gastroenterology-and-endoscopy/dr-joseph-brasco-5-points-on-fecal-microbiota-transplant-in-an-asc.html
I had a huge dose of antibiotics in 1993, and not long after developed bleeding and pain, and was diagnosed with UC.
ReplyDeleteWithin a year my bowel had perforated, nearly killing me and I had a total colectomy.
I often wonder if it was infact due to the antibiotics that my bowel became diseased. Maybe it was C-diff and not UC, but the Dr's didn't know.
Anyway I have had a W pouch since 1998 and I suffer from chronic pouchitis. I often wonder if a fecal transplant would help pouchitis.
Have you ever heard of the transplant being performed on a pouchitis patient?
Hi Vee,
DeleteMy colon perforated as well and I've had a J-pouch since 97 and the past two years I've been suffering from something but they haven't been able to determine if it is Chronic pouchitis, Ulcerative Colitis, or Crohn's disease. I have recently started anti-map therapy and now seem to be in remission!!! I don't know if a fecal transplant would help in your case but I'll make sure the doctor reads your question and we get a response!
Vee
ReplyDeleteSince you do not have a colon... fecal transplant unlikely to be of benefit....
More aggressive treatment of the Pouchitis versus treatment for Crohn's would be the direction I would go in...
Dietary modification may also be helpful.
JB
Hi Dr
ReplyDeleteI Called your office and they asked me to send a note thru web. I know you offer FMT to the C diff patients, but can you also help with UC also ? I am from atlanta area and unfortunately got C diff and UC.
I am alerting Dr. B to this comment so he can respond.
ReplyDelete-Lori
Sorry for the run-around
ReplyDeleteCurrently we are not doing FMT for Ulcerative Colitis...although I am interested! There are a few trials throughout the country looking at this. Dr. Borody in Sydney has used them with good success.
The problem is that one enema will NOT be enough.... it requires multiple enemas over several weeks to see a response with UC.
There is a web-site fecalinfusions.com sponsored by a Sky Curtis....she offers protocols on how to do this.... it is not easy and may be difficult to do without a physicians assistance (Curtis actually suggests a course of Prednisone during the initial infusions...)
I have (2) patients following this protocol and we are starting to see results..but it took almost a MONTH of daily enemas to start seeing improvement.....
As far as the C.diff component very tricky because of the colonic inflammation associated with the UC....higher probability of bacterial translocation and a reaction to the enema itself..... I would certainly be willing to consider treating you, if you still have a (+) C. diff toxin....but this likely will not be as straight forward as our other C. diff cases.
Hello, My name is Phillip and I was diagnosed in september of 2001 with Crohn's disease. This happened not too long after a bout of blood poisoning running from a fingernail infection, which required a week long series of intramuscular injections of Rocephin. To make matters worse, the blood poisoning recurred and the very next week I was back in the doctors office for another week long series of these same injections. within a week of the last injection, I begin to experience painful cramping, constipation, and slight bouts of nausea. Soon after that I went to the emergency room with the pain being too much to handle, and sure enough, after CT scans and xrays, I was diagnosed with Crohns. For years, I tried medications, which helped somewhat, but left me feeling that the long term effects of these meds, such as allopurinol and Asacol might wind up being worse than the condition itself. I wound up in the hospital after losing 50 lbs in one month, with a perforation of my small intestine. I was able to clinically heal without having surgery from that bout with treatments of levaquin and Tequin, which they gave me for all 11 days while hospitalized. After this, I began to explore alternative methods to treat my crohns, as modern medicine seemed to lack any definitive answer for my condition. I basically just lived with the pain and intermittent flareups associated with the condition for years on end. I then went back to my Gastroenterologist for a colonoscopy, which showed that my small intestine was sticking together in the area of the terminal ileum. After the procedure, my doctor proposed the use of remicade, which was touted as a new superdrug which was helping many people achieve remission. I then went home and researched this new medicine, only to find out that among other terrible potential side effects was leukemia. After reading this, I went back for my follow up after the colonoscopy to tell the doctor that I had researched a preventative diet called the SCD diet, and that I would like to try it for 6 months. I went from around 172 lbs back to my normal weight of 200 lbs...I was able to sleep again after years of torment and tylenol taking to get some semblance of it. It was really a godsend. But after about 18 months of the diet, and continuing to be my OWN advocate in this battle with crohn's I came upon reading about Fecal infusions. It makes perfect sense. Before those massive doses of rocephin I mentioned, I was a perfectly healthy person. Right after the last injection, I began to experience the symptoms of crohns. I do beleive that this therapy is the answer to my prayers, what the rocephin killed in my large and small intestine, I can restore by receiving these FMT treatments. So, basically, I wanted to know the cost of the treatment, the easiest possible route in curing this ailment. I live in Miami, Florida and I have been reviewing my options. Whether it be flying to another state for the treatments, or administering them myself, I know this treatment will work. I just wanted to get some feedback based on what I have explained and ask you Dr. Brasco, what you would recommend.
ReplyDelete